Isaac may be the son of Seth and Harriott.

In 1850, on January 2nd, Isaac married Leodicea Nelson Holt in Carroll County, MS.

1850 Census, Carroll Co., MS, Sept. 13th:
Family #265
Isaac M Rundell / age 22 / farmer / b. AR+
Leodicia N ....... / age 19 / ......... / b. SC
John Rundell ... / age 15 / .......... / b. MS

1860 Census, Cherokee Co., TX, July 3rd:
Family #528
Isaac N* Rundle* / age 32 / farmer / b. MS+
Leodieis* ........ / age 31*/ Hkeeper / b. SC
Malinda F ........ / age 09 / ............ / b. MS
Harriet E ......... / age 07 / ............ / b. MS
Israel S ........... / age 04 / ............ / b. MS
Saml E* .......... / age 01 / ............. / b. TX
Wm l .... Holt ... / age 28 / ...clerk... / b. SC

1870 Census, Bosque Co., TX, August 3rd:
Family #660 [Isaac deceased, no birthplace]
Leodicea Rundell / age 37* / keeps H / b. SC
Israel .............. / age 14 / ............. / b. MS
Samuel ........... / age 11 / .............. / b. TX
Sarah J ........... / age 08 / .............. / b. TX
Mary J ............ / age 03 / .............. / b. TX

1880 Census, Bosque Co., TX, June 5th:
Family #138 [Isaac deceased, ..... b. LA+]
Rundell, L. N. / age 50* / farmer / b. SC
Israel S ....... / age 25* / laborer / b. MS
Samuel I ..... / age 20* / laborer / b. TX
John W ....... / age 16 / ..laborer / b. TX
Mary J ........ / age 13 / ............ / b. TX

[*known census inaccuracy]
[+census discrepancy]

[Mary J (Mary Eugenia?) became Minnie E Bender according to Leodicea's obituary. Minnie's death certificate states that her parents were "Marian" Rundell and Dicey Holt. Several of Isaac's descendants were named Marion, and it may have been his middle name.]

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CHILDREN
Malinda ................ (1851 - unknown)
Harriet "Hattie" E ...(1853 - 1913)
Israel Seth ........... (1855 - 1931)
Samuel Isaac ........(1859 - 1926)
Sarah .................. (1861 - 1877)
John William .........(1864 - 1907)
Mary "Minnie" E .....(1866 - 1959)